Accurate protein structure modeling using sparse NMR data and homologous structure information
نویسندگان
چکیده
منابع مشابه
Accurate protein structure modeling using sparse NMR data and homologous structure information.
While information from homologous structures plays a central role in X-ray structure determination by molecular replacement, such information is rarely used in NMR structure determination because it can be incorrect, both locally and globally, when evolutionary relationships are inferred incorrectly or there has been considerable evolutionary structural divergence. Here we describe a method tha...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1202485109